In order to spread awareness about recent advances in medicinal plants & natural products science, this post series is intended to highlight some of the recently published research in the literature. Today’s highlight:
Bioassay-guided isolation of anti-inflammatory and antinociceptive metabolites among three Moroccan Juniperus leaves extract supported with in vitro enzyme inhibitory assays.
El Jemli M, Ezzat SM, Kharbach M, Mostafa ES, Radwan RA, El Jemli Y, El-Guourrami O, Ahid S, Cherrah Y, Zayed A, Alaoui K. J Ethnopharmacol. 2024 Sep 15;331:118285. doi: 10.1016/j.jep.2024.118285. Epub 2024 May 3. PMID: 38703873
This research investigates the anti-inflammatory and antinociceptive (pain-relieving) effects of bioactive compounds isolated from the leaves of three Moroccan Juniperus species.
Using a bioassay-guided approach, the researchers identified specific metabolites that contribute to these therapeutic effects, as confirmed through in vitro enzyme inhibitory assays.
These assays helped pinpoint compounds that effectively inhibit enzymes associated with inflammation and pain pathways.
The findings highlight the potential of Juniperus leaves as natural sources of anti-inflammatory and analgesic agents, which may have applications in treating inflammatory and pain-related conditions.
Link to abstract: https://lnkd.in/g-dBAfxu
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