Continuing this new series…
Scientists have unveiled a remarkable genetic breakthrough-
Canadian Moonseed (Menispermum canadense) is the first known plant capable of naturally adding a chlorine atom to an organic molecule.
➡️ This discovery is important because it demonstrates a previously unknown plant biosynthetic pathway, deepens our understanding of the broader role of chlorine in natural systems, and paves the way for sustainable drug development, leveraging nature’s own solutions to complex chemical challenges.
Researchers traced the evolutionary origin of this unique enzymatic ability, discovering how a once-typical plant enzyme evolved to perform a chemical reaction (chlorination) previously thought impossible in the plant kingdom.
The phenomena centers on the enzyme dechloroacutumine halogenase (DAH), which enables the biosynthesis of the chlorinated alkaloid acutumine: compounds with promising medicinal properties, including selective anticancer activity and potential neurological applications.
This work not only highlights the astonishing resourcefulness of plant evolution, but also exemplifies how decoding nature’s “chemical toolkits” could revolutionize the creation of future medicines and inspire the next generation of biotechnology innovations.
Gratitude for the to the dedicated Researchers of the world whose tireless curiosity and commitment continue to pave new paths for human health and planetary well-being.
Reference:
Weng, J.K. et al. (2023). “Canadian moonseed produces a halogenated alkaloid via an evolved plant halogenase.” Science Advances.
Discovery Spotlight: Chlorine Addition in Plants ⚛️ 🌿
