In order to spread awareness about recent advances in medicinal plants & natural products science, this post series is intended to highlight some of the recently published research in the literature. Today’s highlight:
Revealing the mechanism of Dahuang Huanglian Xiexin Decoction attenuates dysbiosis via IL-17 signaling pathway based on network pharmacology and experimental validation.
Ren T, et al. J Ethnopharmacol. 2024
This research investigates the mechanism by which Dahuang Huanglian Xiexin Decoction (DHXD) mitigates gut microbiota dysbiosis through the IL-17 signaling pathway, using a combination of network pharmacology and experimental validation.
By identifying active compounds and their molecular targets, the study reveals that DHXD modulates IL-17-related pathways to restore gut microbial balance and reduce inflammation.
Experimental results confirm these findings, showing improved gut health and decreased inflammatory markers in models of dysbiosis.
This integrative approach provides insight into the therapeutic effects of DHXD and its potential as a treatment for microbiota-related disorders.
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Dysbiosis & the Dahuang Huanglian Xiexin Decoction
