Eugenol- Important Bioactive From Plants!

Eugenol is a phenylpropene, a type of phenolic compound which is a major component of clove oil (Syzygium aromaticum) with a distinct clove-like scent. Eugenol is also found in significant amounts in other plants, such as basil (Ocimum basilicum), nutmeg (Myristica fragrans), and bay leaf (Laurus nobilis) and contribute to the flavor and scent profiles of these plants.

Among its possible health benefits:

·     Antimicrobial
·     Antiinflammatory
·     Antioxidant
·     Anesthetic
·     Anticancer
·     Antispasmodic
·     Neuroprotective

A recently published study summarized the anesthetic properties and potential applications of eugenol. It was explained how eugenol exhibits local anesthetic effects primarily through the inhibition of voltage-gated sodium channels in sensory neurons, which are crucial for pain signal transmission.

This action results in reduced pain perception and has led to the development of eugenol-based topical anesthetics for dental and other medical uses. Additionally, eugenol’s incorporation into novel delivery systems, like calcium citrate nanoparticles, is being studied for enhancing its effectiveness and stability for clinical applications​.


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*This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician.

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