Ergothioneine-

Important Bioactive From Foods!

Ergothioneine is a naturally occurring amino acid derivative characterized by a unique sulfur-containing imidazole ring, which exists in a stable tautomeric form. This compound is particularly notable for its presence in edible mushrooms—such as shiitake and oyster mushrooms—and can also be found in trace amounts in some cereals and legumes, highlighting its dietary significance.

Among its possible health benefits:

·     Antioxidant

·     Aging

·     Mitochondrial Function

·     Anti-inflammatory

·     Cellular Protection

·     Neuroprotective

·     Metal Chelation

A compelling recent study, published in 2021, explored ergothioneine’s potential to enhance cellular resilience in aging models. The researchers found that supplementation with ergothioneine significantly reduced markers of oxidative stress and improved mitochondrial function in aged laboratory mice, suggesting that this compound might play a critical role in mitigating age-related cellular decline. This study adds to a growing body of evidence indicating that ergothioneine could be a promising candidate for future therapeutic strategies aimed at combating neurodegeneration and other chronic diseases.

#bioactives

#fungi

#mushrooms

#chemistry

#foodasmedicine

#aging

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