Taxifolin is a flavonoid that shares a structural similarity with quercetin but differs in having an additional hydrogen atom, which gives it a dihydroflavonol structure. Taxifolin is found in Siberian larch (Larix sibirica), Douglas fir (Pseudotsuga menziesii), Milk thistle (Silybum marianum), Onion (Allium cepa), Grapes (Vitis vinifera), among other plants. It also is important as it serves as the flavonoid moiety for several other important bioactives that are flavonolignans, such as silymarin.
Among its possible health benefits:
· Antioxidant
· Antiinflammatory
· Anticancer
· Cardioprotective
· Neuroprotective
· Hepatoprotective
· Antimicrobial
· Skin protective (UV-protective)
Taxifolin has shown promising inhibitory activity in a number of conditions, including cardiovascular events, microbial infection, liver disease, and malignancies. For example, one study investigated the cardioprotective effects of taxifolin, particularly focusing on its ability to protect against ischemia-reperfusion injury, which is damage caused by the restoration of blood flow after a heart attack. The study demonstrated that taxifolin significantly reduced oxidative stress and inflammation in heart tissues, which helped minimize cellular damage. This was attributed to its ability to modulate several key signaling pathways involved in oxidative stress, including the NF-κB pathway.
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*This post is for educational purposes only. It is not intended to diagnose, cure or treat any disease. Always seek medical advice directly through consultation with a health professional.
Taxifolin- Important Bioactive From Plants!
