In order to spread awareness about recent advances in medicinal plants & natural products science, this post series is intended to highlight some of the recently published research in the literature. Today’s highlight:
An O-methylflavone from Artemisia afra kills non-replicating hypoxic Mycobacterium tuberculosis. Kellogg JJ, Alonso MN, Jordan RT, Xiao J, Cafiero JH, Bush T, Chen X, Towler M, Weathers P, Shell SS. J Ethnopharmacol. 2024 Oct 28;333:118500. Epub 2024 Jun 27. PMID: 38944359
This research investigates a compound, an O-methylflavone isolated from Artemisia afra, and its efficacy against Mycobacterium tuberculosis under low-oxygen, non-replicating conditions—similar to latent TB infections.
O-methylflavone demonstrated the ability to kill hypoxic TB cells effectively, suggesting its potential as a promising alternative or adjunct in TB treatment, particularly for drug-resistant or latent forms.
The findings support further exploration of Artemisia afra derivatives as viable options in addressing tuberculosis.
Full Text Link: https://lnkd.in/grw69YMS
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Breaking Research: Artemisia Afra & Tuberculosis
